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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 1
2004 2
2005 2
2006 2
2007 2
2008 4
2009 1
2010 1
2011 4
2012 3
2013 4
2014 8
2015 4
2016 7
2017 5
2018 9
2019 9
2020 6
2021 2
2022 9
2023 4
2024 2

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83 results

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Page 1
Histological evaluation in biliary diseases.
Saffioti F, Vieira Motta R, Quaglia A. Saffioti F, et al. Curr Opin Gastroenterol. 2023 Mar 1;39(2):75-82. doi: 10.1097/MOG.0000000000000908. Epub 2023 Jan 4. Curr Opin Gastroenterol. 2023. PMID: 36821454 Review.
Quantification of fibrosis with collagen proportionate area can improve risk stratification and could be particularly useful to assess treatment response in PSC.Gene sequencing on cytology and intrabiliary biopsy may improve risk stratification for cholangiocarcinoma. Genetic var …
Quantification of fibrosis with collagen proportionate area can improve risk stratification and could be particularly useful to assess treat …
ABCB4 Gene Aberrations in Human Liver Disease: An Evolving Spectrum.
Reichert MC, Lammert F. Reichert MC, et al. Semin Liver Dis. 2018 Nov;38(4):299-307. doi: 10.1055/s-0038-1667299. Epub 2018 Oct 24. Semin Liver Dis. 2018. PMID: 30357767 Review.
Dysfunction of this transporter due to ABCB4 gene variants can cause liver diseases and has been called ABCB4 deficiency. ...Recently, increasing evidence from genome-wide association studies is emerging on associations of ABCB4 variants with hepatobiliary ma …
Dysfunction of this transporter due to ABCB4 gene variants can cause liver diseases and has been called ABCB4 deficiency. ...R …
ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth.
Kiehl S, Herkt SC, Richter AM, Fuhrmann L, El-Nikhely N, Seeger W, Savai R, Dammann RH. Kiehl S, et al. Sci Rep. 2014 Nov 4;4:6899. doi: 10.1038/srep06899. Sci Rep. 2014. PMID: 25367630 Free PMC article.
Hypermethylation of the ABCB4 CpG island promoter occurred in 16 out of 26 (62%) human cancer cell lines. ...Hypermethylation of Abcb4 occurred also in murine cancer, but was not found in normal tissues. ...
Hypermethylation of the ABCB4 CpG island promoter occurred in 16 out of 26 (62%) human cancer cell lines. ...Hypermethylation of A …
Variants in ABCB4 (MDR3) across the spectrum of cholestatic liver diseases in adults.
Stättermayer AF, Halilbasic E, Wrba F, Ferenci P, Trauner M. Stättermayer AF, et al. J Hepatol. 2020 Sep;73(3):651-663. doi: 10.1016/j.jhep.2020.04.036. Epub 2020 May 4. J Hepatol. 2020. PMID: 32376413 Free article. Review.
The ATP binding cassette subfamily B member 4 (ABCB4) gene on chromosome 7 encodes the ABCB4 protein (alias multidrug resistance protein 3 [MDR3]), a P-glycoprotein in the canalicular membrane of the hepatocytes that acts as a translocator of phospholipids into bile …
The ATP binding cassette subfamily B member 4 (ABCB4) gene on chromosome 7 encodes the ABCB4 protein (alias multidrug resistan …
Extrahepatic manifestations of progressive familial intrahepatic cholestasis syndromes: Presentation of a case series and literature review.
Pfister ED, Dröge C, Liebe R, Stalke A, Buhl N, Ballauff A, Cantz T, Bueltmann E, Stindt J, Luedde T, Baumann U, Keitel V. Pfister ED, et al. Liver Int. 2022 May;42(5):1084-1096. doi: 10.1111/liv.15200. Epub 2022 Mar 15. Liver Int. 2022. PMID: 35184362 Review.
METHODS: We performed a literature search for extrahepatic manifestations of PFIC associated with pathogenic gene variants in ATP8B1, ABCB11, ABCB4, TJP2, NR1H4 and MYO5B. To illustrate the extrahepatic symptoms described in the literature, PFIC cases from our centres were …
METHODS: We performed a literature search for extrahepatic manifestations of PFIC associated with pathogenic gene variants in ATP8B1, ABCB11 …
Genetics of gallstone disease revisited: updated inventory of human lithogenic genes.
Weber SN, Bopp C, Krawczyk M, Lammert F. Weber SN, et al. Curr Opin Gastroenterol. 2019 Mar;35(2):82-87. doi: 10.1097/MOG.0000000000000511. Curr Opin Gastroenterol. 2019. PMID: 30608254 Review.
A second ABC transporter, the hepatic phosphatidylcholine translocase ABCB4, increases the risk for gallstone disease, gallbladder cancer and chronic liver diseases in general, whereas the common PNPLA3 risk variant p.I148M decreases gallstone risk. ...
A second ABC transporter, the hepatic phosphatidylcholine translocase ABCB4, increases the risk for gallstone disease, gallbladder ca …
Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells.
Duan Z, Brakora KA, Seiden MV. Duan Z, et al. Mol Cancer Ther. 2004 Jul;3(7):833-8. Mol Cancer Ther. 2004. PMID: 15252144
In this study, we demonstrate that paclitaxel-resistant cell lines overexpress both ABCB1 and ABCB4 (MDR3). To evaluate the role of these transporters in paclitaxel-resistant ovarian cancer cells, small interference RNAs (siRNAs) were used to target ABCB1 and ABCB4 …
In this study, we demonstrate that paclitaxel-resistant cell lines overexpress both ABCB1 and ABCB4 (MDR3). To evaluate the role of t …
Low-Phospholipid Associated Cholelithiasis (LPAC) syndrome: A synthetic review.
Goubault P, Brunel T, Rode A, Bancel B, Mohkam K, Mabrut JY. Goubault P, et al. J Visc Surg. 2019 Sep;156(4):319-328. doi: 10.1016/j.jviscsurg.2019.02.006. Epub 2019 Mar 26. J Visc Surg. 2019. PMID: 30922600 Free article. Review.
Low-Phospholipid Associated Cholelithiasis (LPAC) is a genetic disease responsible for the development of intrahepatic lithiasis. It is associated with a mutation of the ABCB4 gene which codes for protein MDR3, a biliary carrier. As a nosological entity, it is defined by p …
Low-Phospholipid Associated Cholelithiasis (LPAC) is a genetic disease responsible for the development of intrahepatic lithiasis. It is asso …
ABCB4/MDR3 gene mutations and cholangiocarcinomas.
Tougeron D, Fotsing G, Barbu V, Beauchant M. Tougeron D, et al. J Hepatol. 2012 Aug;57(2):467-8. doi: 10.1016/j.jhep.2012.01.025. Epub 2012 Mar 2. J Hepatol. 2012. PMID: 22387667 Free article. No abstract available.
Pharmacologic Antagonization of Cannabinoid Receptor 1 Improves Cholestasis in Abcb4(-/-) Mice.
Helmrich N, Roderfeld M, Baier A, Windhorst A, Herebian D, Mayatepek E, Dierkes C, Ocker M, Glebe D, Christ B, Churin Y, Irungbam K, Roeb E. Helmrich N, et al. Cell Mol Gastroenterol Hepatol. 2022;13(4):1041-1055. doi: 10.1016/j.jcmgh.2021.12.013. Epub 2021 Dec 23. Cell Mol Gastroenterol Hepatol. 2022. PMID: 34954190 Free PMC article.
We hypothesized that the pharmacologic antagonization of CB1 receptor improves cholestasis in Abcb4(-/-) mice. METHODS: After weaning, male Abcb4(-/-) mice were treated orally with rimonabant (a specific antagonist of CB1) or ACEA (an agonist of CB1) until up to 16 …
We hypothesized that the pharmacologic antagonization of CB1 receptor improves cholestasis in Abcb4(-/-) mice. METHODS: After weaning …
83 results